Anti-CKMT1 Monoclonal Antibody

品牌：solarbio | 货号：K000065M

英文名称	Anti-CKMT1 Monoclonal Antibody
宿主	Mouse
别名	CKMT;CKMT1;UMTCK
应用	WB
稀释比例	WB 1:1000.
交叉反应	Human Mouse
蛋白分子量	47kDa
Gene ID	1159
保存	Store at -20°C. Avoid freeze / thaw cycles.
储存液	Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法	Affinity purification
亚型	IgG1
免疫原	Purified recombinant human CKMT1 protein fragments expressed in E.coli.
性状	液体
Public Immunogen Range	Purified recombinant human CKMT1 protein fragments expressed in E.coli.
Subcellular Locations	Intermembrane side Mitochondrion inner membrane Peripheral membrane protein
Swiss Prot	P12532
克隆号	1A6-C7-G10
克隆类型	Monoclonal Antibody
背景资料	Mitochondrial creatine (MtCK) kinase is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. It belongs to the creatine kinase isoenzyme family. It exists as two isoenzymes, sarcomeric MtCK and ubiquitous MtCK, encoded by separate genes. Mitochondrial creatine kinase occurs in two different oligomeric forms: dimers and octamers, in contrast to the exclusively dimeric cytosolic creatine kinase isoenzymes. Many malignant cancers with poor prognosis have shown overexpression of ubiquitous mitochondrial creatine kinase; this may be related to high energy turnover and failure to eliminate cancer cells via apoptosis. Ubiquitous mitochondrial creatine kinase has 80% homology with the coding exons of sarcomeric mitochondrial creatine kinase. Two genes located near each other on chromosome 15 have been identified which encode identical mitochondrial creatine kinase proteins.