TPO (Human) Recombinant Protein
产品名称： TPO (Human) Recombinant Protein
英文名称： TPO (Human) Recombinant Protein
产品编号： P4059
产品价格： 0
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围： null
亚诺法生技股份有限公司（Abnova)
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- 邮编 : 11493
- 所在区域 : 台湾
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- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Human TPO (P07202, 174 amino acids) partial recombinant protein expressed in Escherichia coli.
- Form:
- Lyophilized
- Preparation Method:
- Escherichia coli expression system
- Purity:
- ≥ 98% by SDS-PAGE and HPLC
- Endotoxin Level:
- < 0.1 ng/ug
- Activity:
- The ED50 as determined by the dose-dependent stimulation of the proliferation of human MO7e cells was found < 1 ng/mL, corresponding to a specificactivity of > 1 x 106 IU/mg.
- Storage Buffer:
- No additive
- Storage Instruction:
- Store at -20°C on dry atmosphere.
After reconstitution with sterilized water, store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Application Image
- Functional Study
- SDS-PAGE
- Entrez GeneID:
- 7173
- Protein Accession#:
- P07202
- Gene Name:
- TPO
- Gene Alias:
- MSA,TPX
- Gene Description:
- thyroid peroxidase
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a membrane-bound glycoprotein. The encoded protein acts as an enzyme and plays a central role in thyroid gland function. The protein functions in the iodination of tyrosine residues in thyroglobulin and phenoxy-ester formation between pairs of iodinated tyrosines to generate the thyroid hormones, thyroxine and triiodothyronine. Mutations in this gene are associated with several disorders of thyroid hormonogenesis, including congenital hypothyroidism, congenital goiter, and thyroid hormone organification defect IIA. Multiple transcript variants encoding distinct isoforms have been identified for this gene. Additional splice variants have been described but their biological natures have not been determined. [provided by RefSeq
- Other Designations:
- OTTHUMP00000115304,OTTHUMP00000115536,thyroid microsomal antigen,thyroperoxidase